Ranexa 375mg

What is Ranexa and how is it used?
Ranexa 375mg is a prescription medicine used to treat the symptoms of chest pain (Angina). Firstly, Ranexa may be used alone or with other medications.

Furthermore, Ranexa belongs to a class of drugs called Antianginal, Non-nitrates.

It is not know if Ranexa is safe and effective in children younger than 18 years of age.

What are the possible side effects of Ranexa?

Ranexa may cause serious side effects including:

lightheadedness,
fast or pounding heartbeats,
fluttering in your chest,
little or no urination,
painful or difficult urination,
swelling in your feet or ankles,
feeling tired, and
shortness of breath
Get medical help right away, if you have any of the symptoms listed above.

The most common side effects of Ranexa include:

nausea,
constipation,
headache, and
dizziness
Tell the doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Ranexa. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

DESCRIPTION

RANEXA (ranolazine) Extended-release Tablets

Secondly, Ranolazine is a racemic mixture, chemically described as 1-piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, (±)-. It has an empirical formula of C24H33N3O4, a molecular weight of 427.54 g/mole, and the following structural formula:

RANEXA® (ranolazine) Structural Formula Illustration
Ranolazine is a white to off-white solid. Ranolazine is soluble in dichloromethane and methanol; sparingly soluble in tetrahydrofuran, ethanol, acetonitrile, and acetone; slightly soluble in ethyl acetate, isopropanol, toluene, and ethyl ether; and very slightly soluble in water.

RANEXA tablets contain 500 mg or 1000 mg of ranolazine and the following inactive ingredients: carnauba wax, hypromellose, magnesium stearate, methacrylic acid copolymer (Type C), microcrystalline cellulose, polyethylene glycol, sodium hydroxide, and titanium dioxide. Additional inactive ingredients for the 500 mg tablet include polyvinyl alcohol, talc, Iron Oxide Yellow, and Iron Oxide Red; additional inactive ingredients for the 1000 mg tablet include lactose monohydrate, triacetin, and Iron Oxide Yellow.